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Exenatide in obese or overweight patients without diabetes: A systematic review and meta-analyses of randomized controlled trials
It works through two mechanisms: inhibiting the enzyme tyrosinase (which is essential for melanin synthesis) and shifting the melanin production pathway from eumelanin (darker pigment) to pheomelanin (lighter pigment)
62 Three metal ions including two Zn 2+ and one Mg 2+ at the active site are essential for enzyme activity
Abnormal glucose metabolites in cerebrospinal fluid (CSF) and functional imaging of cerebral glucose metabolism using fluorodeoxyglucose positron emission tomography (FDG-PET) hold promise for early and differential diagnosis of PD [14, 15]
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